We have been invited to apply to join the Marathon of Hope Cancer Centres Network (MoHCCN) as a designated consortium from Atlantic Canada. The MoHCCN’s mission is to bring together leading cancer centres, clinics, and academic institutions across Canada to collaborate on precision medicine research to benefit cancer patients and drive innovation. For more details on MoHCCN, please visit https://www.tfri.ca/our-research/marathon-of-hope In Atlantic Canada we share the MoHCCN vision to unite Canada to cure cancer. We are aligned with the MoHCCN mission to create a national network that applies world-leading science to cancer care, with a focus on precision medicine. We have rallied our region’s leading cancer researchers, institutions and care facilities to unite around this vision and mission through our active ACC demonstration project and the assembly of this proposal to join the MoHCCN as a full designated consortium. The ACC will make the following key contributions to the MoHCCN in the next three years: • Contribution of 900 “gold cohort” cancer cases for comprehensive biological and clinical profiling • Engagement with rural and underserved communities to deliver precision oncology opportunities • Engagement with Indigenous communities to develop a framework for collaboration • Enhanced opportunities in precision cancer medicine for ACC trainees and new investigators • Regional projects with the potential for national leadership in our areas of cancer research strength, including o Implementation of precision medicine in the clinical setting o Immunology o Metabolism o Biomarkers